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Expression analysis of genes responsible for amino acid biosynthesis in halophilic bacterium <i style="mso-bidi-font-style:normal">Salinibacter ruber</i>

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Title Expression analysis of genes responsible for amino acid biosynthesis in halophilic bacterium Salinibacter ruber
 
Creator Sanjukta, R K
Farooqi, Md. Samir
Rai, Niyati
Rai, Anil
Sharma, Naveen
Mishra, Dwijesh C
Singh, Dhananjaya P
 
Subject Synonymous codon usage
Multi-variate statistical analysis
Mutational bias
Salinibacter rubber
Halophilic bacterium
 
Description 177-185
The degeneracy
of the genetic code allows for multiple codons to encode the same amino acid.
However, alternative codons and amino acids are used unevenly among genes, a
phenomenon termed codon-usage bias. Genes regulating amino acid biosynthesis of
Salinibacter ruber, an extremely
halophilic bacterium were studied in order to determine the synonymous codon
usage patterns. Factors responsible for codon usage variation among the genes
were investigated using codon usage indices and multi-variate statistical
approach. Overall codon usage data analysis indicated that codons ending in G
and/or C were predominant among the genes. Multi-variate statistical analysis
showed that there was a single major trend in the codon usage variation among
the genes, which had a strong positive correlation (r = 0.93, P
 
Date 2013-06-04T12:55:42Z
2013-06-04T12:55:42Z
2013-06
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/18686
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.50(3) [June 2013]