Record Details

Compositional correlation and codon usage studies in <i>Buchnera aphidicola</i>

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Compositional correlation and codon usage studies in Buchnera aphidicola
 
Creator Gupta, S K
Bhattacharyya, T K
Ghosh, T C
 
Description 35-48
Compositional distributions in three
different codon positions as well as codon usage biases of all available DNA sequences
of Buchnera aphidicola genome have been analyzed. It was observed that GC
levels among the three codon positions is I>II>III as observed in other
extremely high AT rich organisms. B. aphidicola being an AT rich organism
is expected to have A and/or T at the third positions of codons. Overall codon usage
analyses indicate that A and/or T ending codons are predominant in this organism
and some particular amino acids are abundant in the coding region of genes. However,
multivariate statistical analysis indicates two major trends in the codon usage
variation among the genes; one being strongly correlated with the GC contents
at the third synonymous positions of codons, and the other being associated with
the expression level of genes. Moreover, codon usage biases of the highly expressed
genes are almost identical with the overall codon usage biases of all the genes
of this organism. These observations suggest that mutational bias is the main

factor in determining the codon usage
variation among the genes in B. aphidicola.
 
Date 2013-07-15T06:06:56Z
2013-07-15T06:06:56Z
2002-02
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/19746
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.39(1) [February 2002]