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Studies on the microstructure of bile salt aggregates in aqueous <i>n</i>-alkanol solutions by Small Angle Neutron Scattering

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Title Studies on the microstructure of bile salt aggregates in aqueous n-alkanol solutions by Small Angle Neutron Scattering
 
Creator Santhanalakshmi, J
Shanthalakshmi, G
Aswal, V K
Goyal, P S
 
Description 170-178
Small Angle Neutron Scattering (SANS) measurements
on two bile salt micelle systems sodium cholate (NaC) and sodium deoxycholate (NaDC)
each 0.1 M in the absence and presence of 0.05 M 1-butanol, 1-pentanol,
1-hexanol and 1-octanol were carried out in D2O at ambient conditions
(25°C). The scattering cross-section as a function of wave vector transfer (Q)
showed the presence of correlation peaks characteristic of strong inter micellar
interactions. The correlation peak positions were shifted to low Q values in the
presence of n-alkanols for both NaC and NaDC micelles. Best fit curves of
SANS were produced by applying Hayter-Penfold analysis considering monodisperse
ellipsoid model for the micelles. The best fits were found for constant semi-minor
axis=8Å with an increasing semi -major axis for increasing n-alkanol chain
lengths. The micellar growths in presence of n -alkanols were studied using
the ESR correlation time measurements on suitable spin probe incorporated micelles.
The growth parameter and the hydrodynamic radii values were found to be agreeable
with SANS data. Intermicellar interaction potentials seem to increase with the
Cn of n -alkanols.
 
Date 2013-07-15T08:50:01Z
2013-07-15T08:50:01Z
2002-06
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/19774
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.39(3) [June 2002]