Record Details

Ornithine α-ketoglutarate modulates the levels of antioxidants and lipid peroxidation products in ammonium acetate treated rats

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Ornithine α-ketoglutarate modulates the levels of antioxidants and lipid peroxidation products in ammonium acetate treated rats
 
Creator Dakshayani, K B
Velvizhi, S
Subramanian, P
 
Description 422-424
The effects of ornithine α-ketoglutarate (OKG)
on ammonium acetate induced hepatotoxicity were studied in experimental rats. The
levels of urea, non-protein nitrogen and thiobarbituric acid reactive substances
were significantly increased in ammonium acetate treated rats ; but these levels
were significantly decreased in ammonium acetate-OKG treated rats. Similar patterns
were observed in the levels of free fatty acids, triglycerides and phospholipids.
Furthermore, non-enzymatic (reduced glutathione) and enzymatic (glutathione peroxidise,
superoxide dismutase and catalase) antioxidants were significantly decreased in
ammonium acetate treated rats. When compared with control and were significantly
increased in ammonium acetate-OKG treated rats compared to ammonium acetate treatment
alone.
 
Date 2013-07-15T10:15:10Z
2013-07-15T10:15:10Z
2002-12
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/19789
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.39(6) [December 2002]