Record Details


Field	Value

Title	Wobble base-pairing in codon-anticodon interactions: A theoretical modelling study

Creator	Mangang, S Ulen Lyngdoh, R H Duncan

Description	115-119 The Crick wobble hypothesis attributes the phenomenon of codon degeneracy to a certain impreciseness of pairing between the third base of the codon and the first base of the anticodon. This theoretical study investigates the pairing properties of some wobble bases, including both, observed and unobserved pairs. Some wobble base-pairs are predicted to follow the Watson-Crick pairs in configuration and pairing facility, while others deviate from this norm. The observed U:V pair is unique in that a pairing configuration may be suggested for it wherein the hydrogen-bonding involves the exocyclic 5- carboxy methoxy group of V. By comparing the theoretical data on the configurations of these pairs with the evidence for their existence/non-existence in nature, some guidelines emerge for differentiating between observed and unobserved base pairs on the basis of the pairing configuration.

Date	2013-07-16T06:34:32Z 2013-07-16T06:34:32Z 2001-04

Type	Article

Identifier	0975-0959 (Online); 0301-1208 (Print) http://hdl.handle.net/123456789/19809

Language	en_US

Rights	CC Attribution-Noncommercial-No Derivative Works 2.5 India

Publisher	NISCAIR-CSIR, India

Source	IJBB Vol.38(1-2) [February-April 2001]

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