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Hydrophilic polymeric nanoparticles as drug carriers

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Title Hydrophilic polymeric nanoparticles as drug carriers
 
Creator Ghosh, P K
 
Description 273-282
Polymeric hydrophilic nanoparticles have attracted
attention because of their potential usefulness as drug-carriers in target specific
cells, tissues or nucleus. Applications are expected through injectable, oral, nasal
or ocular routes. Hydrophilic nanoparticles have been prepared that are hydrophilic
on the surface as well as inside the core; particles have also been made that are
hydrophilic on the outer surface but are hydrophobic within the core. External stimuli
responsive hydrophilic nanoparticles are yet another new addition to the spectra
of new materials in drug delivery. Water soluble as well as insoluble drugs can
be entrapped into these polymers by adjusting the hydrophilicity/ hydrophobicity
of the core of the nanoparticles. The review discusses the requirements that
these hydrogel nanoparticles must meet to be effective in drug delivery, and the
importance of the preparative methods for controlling their sizes below 100 nm,
with narrow size distribution.
 
Date 2013-07-16T08:55:29Z
2013-07-16T08:55:29Z
2000-10
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/19833
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.37(5) [October 2000]