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Critical time delay of the pineal melatonin rhythm in humans due to weak electromagnetic exposure

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Title Critical time delay of the pineal melatonin rhythm in humans due to weak electromagnetic exposure
 
Creator Halgamuge, Malka N
 
Subject Melatonin level
Circadian rhythm
Pineal melatonin model
Electromagnetic fields
Health effects
 
Description 259-265
Electromagnetic fields (EMFs) can increase
free radicals, activate the stress response and alter enzyme reactions.
Intracellular signalling is mediated by free radicals and enzyme kinetics is
affected by radical pair recombination rates.
The magnetic field component of an external EMF can delay the
"recombination rate" of free radical pairs. Magnetic fields thus
increase radical life-times in biological systems. Although measured in
nanoseconds, this extra time increases the potential to do more damage.
Melatonin regulates the body's sleep-wake cycle or circadian rhythm. The World
Health Organization (WHO) has confirmed that prolonged alterations in sleep
patterns suppress the body's ability to make melatonin. Considerable cancer rates
have been attributed to the reduction of melatonin production as a result of
jet lag and night shift work. In this study, changes in circadian rhythm and
melatonin concentration are observed due to the external perturbation of
chemical reaction rates. We further analyze the pineal melatonin rhythm and
investigate the critical time delay or maturation time of radical pair
recombination rates, exploring the impact of the mRNA degradation rate on the
critical time delay. The results show that significant melatonin interruption
and changes to the circadian rhythm occur due to the perturbation of chemical
reaction rates, as also reported in previous studies. The results also show the
influence of the mRNA degradation rate on the circadian rhythm’s critical time
delay or maturation time. The results support the hypothesis that exposure to
weak EMFs via melatonin disruption can adversely affect human health.
 
Date 2013-09-01T12:59:09Z
2013-09-01T12:59:09Z
2013-08
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/20873
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.50(4) [August 2013]