Record Details

<span style="mso-bidi-font-family:"Times New Roman"" lang="EN-US">Anti-carcinogenic potential of <i>Euphorbia neriifolia</i> leaves and isolated flavonoid against N-<span style="mso-bidi-font-family:"Times New Roman";mso-fareast-language: ZH-CN" lang="EN-US">N<span style="mso-bidi-font-family:"Times New Roman"" lang="EN-US">itrosodiethylamine<span style="mso-bidi-font-family:"Times New Roman"" lang="EN-US">-induced renal carcinogenesis in mice<span style="mso-bidi-font-weight:bold"> </span></span></span></span></span>

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Anti-carcinogenic potential of Euphorbia neriifolia leaves and isolated flavonoid against N-Nitrosodiethylamine-induced renal carcinogenesis in mice
 
Creator Sharma, Veena
Pracheta
 
Subject N-Nitrosodiethylamine
Euphorbia neriifolia
Antioxidant
Renal carcinogenesis
Flavonoid
BHA
 
Description 521-528
Anti-carcinogenic potential of
hydro-ethanolic extract of Euphorbia
neriifolia (EN) leaves and an isolated flavonoid (ENF) was investigated
against N-Nitrosodiethylamine (DENA)-induced renal carcinogenesis in mice.
Experimental mice were pretreated with 150 and 400 mg/kg body wt of EN, 0.5%
and 1% mg/kg body wt of butylated hydroxylanisole (BHA) as a standard
antioxidant and 50 mg/kg body wt of ENF for 21 days prior to the administration
of a single dose of 50 mg/kg body wt of DENA. Levels of renal markers (urea and
creatinine), xenobiotic metabolic enzymes (Cyt P450 and Cyt b5), lipid
peroxidation (LPO), antioxidants (SOD, CAT, GST and GSH) and other biochemical
parameters — AST, ALT, ALP, total protein (TP), and total cholesterol (TC) were
measured to determine the renal carcinogenesis caused by DENA. DENA
administration significantly (p
 
Date 2013-12-27T11:46:15Z
2013-12-27T11:46:15Z
2013-12
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/25170
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.50(6) [December 2013]