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Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat

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Title Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat
 
Creator Kawahara, Elisa Ito
Maués, Nadine Helena Pelegrino Bastos
Santos, Klinsmann Carolo dos
Barbanera, Pedro Octávio
Braga, Camila Pereira
Fernandes, Ana Angélica Henrique
 
Subject Calorimetry
Nutritional parameters
Oxidative stress
Energy restriction
Myocardium
 
Description 365-371
Caloric restriction, defined as a reduction in calorie
intake below ad libitum, without
malnutrition can have beneficial effects. In this study, we evaluated the
impact of caloric restriction of 30 and 60% on calorimetric parameters and
oxidative stress in cardiac tissue in rats. Rats were randomly divided into 3
groups (n = 8): G1 = control; G2 = rats exposed to dietary restriction
of 30%; and G3 = rats exposed to dietary restriction of 60%. Energy restriction
decreased final body weight, oxidation of carbohydrates and lipid, oxygen
consumption (VO2), carbon dioxide production (VCO2),
resting metabolic rate (RMR), but elevated respiratory quotient (RQ). G3
animals also displayed an imbalance in the oxidant/antioxidant system, as
revealed by the decrease in the lipid hydroperoxide (LH) level and GSH-Px
activity in heart tissue. In conclusion, dietary restriction decreased
oxidative metabolism, as seen by the colorimetric profiles and controlled oxidative stress in cardiac
tissue.


 
Date 2014-11-12T11:00:46Z
2014-11-12T11:00:46Z
2014-10
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/29885
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.51(5) [October 2014]