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Antioxidant potential of different grape cultivars against Fenton-like reagent-induced liver damage <i style="mso-bidi-font-style:normal">ex-vivo</i>

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Title Antioxidant potential of different grape cultivars against Fenton-like reagent-induced liver damage ex-vivo
 
Creator Singha, Indrani
Das, Subir Kumar
 
Subject Antioxidant
Fenton’s reagent
Fenton-like reagent
Glutathione
Grapes
Liver
Total Antioxidant capacity
 
Description 372-377
The phytochemicals present in the grapes are
responsible for nutraceutical and health benfits due to their antioxidant
properties. These
phytochemicals, however, vary greatly among different cultivars. In this study,
we evaluated the antioxidant potential and protective
role of four different Indian grape (Vitis vinifera) cultivars extracts,
namely Flame seedless (Black grapes), Kishmish chorni (Black with reddish brown), Red
globe (Red) and Thompson seedless mutant (Sonaka, Green) against the
Fenton-like reagent (200 mmole H2O2,
2 mmole ascorbate, 25 mmole FeSO4)-induced
liver damage. Non-enzymatic antioxidants, such as glutathione (GSH) levels and
activities of antioxidant enzymes, such as glutathione S-transferase (GST) and
superoxide dismutase (SOD), as well as total antioxidant capacity (TAC) were
highest in the grape seed, followed by skin and pulp. Among edible parts of
different cultivars, skin of Flame seedless (Black) cultivar showed highest
antioxidant potential, while the Thompson seedless the least potential. These
antioxidants were found to be significantly (P
 
Date 2014-11-12T11:02:19Z
2014-11-12T11:02:19Z
2014-10
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/29886
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.51(5) [October 2014]