Record Details

<i style="mso-bidi-font-style:normal"><span style="font-size:13.0pt; mso-bidi-font-weight:bold" lang="EN-GB">In vitro</span></i><span style="font-size:13.0pt;mso-bidi-font-weight:bold" lang="EN-GB"> anticancer activity of extracts of <i style="mso-bidi-font-style:normal">Mentha</i> Spp. against human cancer cells </span>

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells
 
Creator Sharma, Vikas
Hussain, Shabir
Gupta, Moni
Saxena, Ajit Kumar
 
Subject Mentha Spp.
Cancer cells
SRB assay
 
Description 416-419
In
vitro anticancer potential of methanolic and
aqueous extracts of whole plants of Mentha
arvensis, M. longifolia,
M. spicata and M. viridis at
concentration of 100 µg/ml
was evaluated against eight human cancer cell lines — A-549, COLO-205, HCT-116,
MCF-7, NCI-H322, PC-3, THP-1 and
U-87MG from six different origins (breast, colon, glioblastoma, lung, leukemia
and prostate) using sulphorhodamine blue (SRB) assay. Methanolic extracts of
above-mentioned Mentha Spp. displayed
anti-proliferative effect in the range of 70-97%
against four human cancer cell lines, namely COLO-205, MCF-7, NCI-H322 and
THP-1; however, aqueous extracts were found
to be active against HCT-116 and PC-3. The results indicate
that Mentha Spp. contain certain
constituents with cytotoxic properties which may find use in developing
anticancer agents.
 
Date 2014-11-12T11:08:22Z
2014-11-12T11:08:22Z
2014-10
 
Type Article
 
Identifier 0975-0959 (Online); 0301-1208 (Print)
http://hdl.handle.net/123456789/29893
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJBB Vol.51(5) [October 2014]