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<p><span>Extraction of antibacterial substances, galactofucoidan and alginate successively from the Gulf of Mannar brown seaweed </span><em>Sargassum wightii</em><span> Greville ex J. Agardh</span></p>

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Title Statement <p><span>Extraction of antibacterial substances, galactofucoidan and alginate successively from the Gulf of Mannar brown seaweed </span><em>Sargassum wightii</em><span> Greville ex J. Agardh</span></p>
 
Added Entry - Uncontrolled Name Eluvakkal, T
N, shanthi ; Alagappa Govt. Arts College
Murugan, M
Arunkumar, K ; Phone: 91-4565224521
 
Uncontrolled Index Term Seaweed technology
Sargassum wightii, Galactofucoidan, Antibacterial substances, Alginate.
 
Summary, etc. <span>In the present study, galactose dominated fucoidan was isolated through successive extraction method in alkaline, acid and neutral pH from the brown seaweed </span><em>Sargassum wightii </em><span>Greville ex J. Agardh collected along the Gulf of Mannar (Pamban, India) during March 2011. In this study, crude extracts obtained in chloroform: methanol (1:1 v/v) and 85 % ethanol (at 23°C and 70°C) showed antibacterial activity against</span><em> Xanthomonas axonopodis </em><span>pv</span><em>. citri </em><span>and <em>X. oryzae </em>pv.<em> oryzae</em> which cause canker in citrus and blight of paddy, respectively. Low (<span lang="&quot;EN-GB&quot;">&lt; 3500 Da) and high molecular weight (<span lang="&quot;EN-GB&quot;">&gt; 3500 Da) fucoidans separated through DEAE cellulose 52 column were recorded same proportion of monosugars constituents dominating D-galactose over L-fucose. Spectroscopic studies (IR &amp; NMR) of high molecular weight fucoidan (Fraction, A1H) with high sulphate showed higher anticoagulation activity than low molecular weight fucoidan under <em>in vitro</em> APTT assay. This investigation concludes that successive extraction method yields galactofucoidan (3.62 %), alginate (11.2 %) and antibacterial substances (13.34 %) in the same biomass of brown seaweed <em>S. wightii</em>.</span></span></span><p> </p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2016-02-19 08:35:30
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/3634
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 5, ##issue.no## 3 (2014): September 2014
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJNPR/article/download/3634/7024
 
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