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<span style="&quot;font-size: 11.0pt;" lang="&quot;EN-GB&quot;">Isolation, characterization and quantification of bioactive dibenzylbutyrolactone lignan (-)-cubebin from fruits of <em style="&quot;mso-bidi-font-style: normal&quot;;">Piper cubeba </em>L.f.</span><p> </p>

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Title Statement <span style="&quot;font-size: 11.0pt;" lang="&quot;EN-GB&quot;">Isolation, characterization and quantification of bioactive dibenzylbutyrolactone lignan (-)-cubebin from fruits of <em style="&quot;mso-bidi-font-style: normal&quot;;">Piper cubeba </em>L.f.</span><p> </p>
 
Added Entry - Uncontrolled Name Mulik, M B; Institute of Chemical Technology, Mumbai
Laddha, K S; Institute of Chemical Technology, Mumbai
University Grant Commission-Rajiv Gandhi National Fellowship for Disability (UGC-RGNFD), New Delhi
 
Uncontrolled Index Term Pharmacognosy; phytochemistry; isolation of bioactive dibenzylbutyrolactone lignan
Cubebin; HPLC; Isolation; Piper cubeba L.f 
 
Summary, etc. <span style="&quot;font-size: 11.0pt;" lang="&quot;EN-GB&quot;">The fruits of <em style="&quot;mso-bidi-font-style: normal&quot;;">Piper cubeba </em>L.f. have significance in traditional medicine (Ayurveda) and reports say that its activity is due to major lignan (-)-cubebin, which is a bioactive dibenzylbutyrolactone lignan and possess analgesic, anti-histaminic, antimicrobial and cytotoxic activities. Column chromatography is mostly used for the isolation of lignans from plant sources which is laborous and time consuming process. Therefore, the purpose of this research work is to develop simple and convenient method for isolation of (-)-cubebin from fruits of <em style="&quot;mso-bidi-font-style: normal&quot;;">P cubeba </em>L.f. <span style="&quot;font-size: 11.0pt; font-family: &quot;;">The isolated compound was characterised by thin-layer chromatography (TLC), UV/visible spectroscopy (UV), infrared spectroscopy (IR), mass spectroscopy (MS) and nuclear magnetic resonance spectral analysis (NMR). <span style="&quot;font-size: 11.0pt; font-family: &quot;;" lang="&quot;EN-GB&quot;">Further <span style="&quot;font-size: 11.0pt;">high performance liquid chromatography (<span style="&quot;font-size: 11.0pt;" lang="&quot;EN-GB&quot;">HPLC) was used to quantify (-)-cubebin in chloroform extract of the fruits. </span></span></span></span></span><p> </p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2015-12-02 08:25:01
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/7353
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 6, ##issue.no## 3 (2015): September 2015
 
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