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<p><span>Evaluation of anti-inflammatory activity of </span><em>Dracaena cinnabari</em><span> Balf. f. resin</span></p>

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Title Statement <p><span>Evaluation of anti-inflammatory activity of </span><em>Dracaena cinnabari</em><span> Balf. f. resin</span></p>
 
Added Entry - Uncontrolled Name Gupta, Deepika ; GGS Indraprastha University,Dwarka, New Delhi 110075 INDIA
Verma, Nandini ; Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi, 110007, India.
Das, Hasi R; Institute of Genomics and Integrative Biology, Delhi University Campus, Mall Road, Delhi, 110007, India.
Gupta, Rajinder K; GGS Indraprastha University,Dwarka, New Delhi 110075 INDIA
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Uncontrolled Index Term Natural products
Dracaena cinnabari, Resin, Anti-inflammatory, LPS-stimulated macrophage, Rat paw edema, Homoisoflavan.
 
Summary, etc. <em>Dracaena cinnabari </em><span>Balf. f. (Family- Dracaenaceae) resin is a traditional medicine since ancient times in many cultures. Most of the pharmacological investigations of this</span><em> </em><span>resin have been addressed to its anti-microbial, anti-viral and antioxidant activities. However, anti-inflammatory activity of </span><em>D. cinnabari </em><span>resin is not evaluated so far. The present study indicates that methanol extract of </span><em>D. cinnabari </em><span>resin (MEDC) and one of its components, 4'-hydroxy-7,8-methylenedioxyhomoisoflavan (MHF) inhibited nitrite, TNF-α and IL-6 productions in lipopolysaccharide-stimulated mouse macrophage cell line RAW 264.7 with increase in their concentrations. Anti-inflammatory activities of these treatments were further confirmed by the reduction of rat hind paw edema. These results suggest that MEDC and MHF have potential anti-inflammatory activity at the selected doses.</span>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2016-02-19 08:35:30
 
Electronic Location and Access "application/pdf"
http://op.niscair.res.in/index.php/IJNPR/article/view/4079
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 5, ##issue.no## 3 (2014): September 2014
 
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