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<span>Validation of an analytical methodology for determination of tetracyclines residues in honey by UPLC-MS/MS detection</span><br />

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Title Statement <span>Validation of an analytical methodology for determination of tetracyclines residues in honey by UPLC-MS/MS detection</span><br />
 
Added Entry - Uncontrolled Name Singh, Sarvendra Pratap; Shobhit University, Meerut
Pundhir, Aditya ; Shobhit University, Meerut
Ghosh, Sampat ; Shobhit University, Meerut
 
Uncontrolled Index Term Apiary, Food contamination
Antibiotics, Honey, Solid-phase extraction, Tetracyclines, UPLC-MS/MS.
 
Summary, etc. <span>An analytical method for the quantification of six common tetracyclines and derivatives thereof including tetracycline, 4-epitetracycline, 4-epioxytetracycline, oxytetracycline, 4-epichlortetracycline, chlortetracycline and doxycycline in honey has been validated. The method involved sample preparation in Na</span><sub>2</sub><span>EDTA- McIlvaine buffer, solid phase extraction and quantification by UPLC-MS. A linear proportionality between chromatogram area and analyte concentration (R</span><sup>2</sup><span>&gt; 99 %) was found. Recoveries of metabolites from samples fortification at LOQ level were higher than 83 %. Decision limit and detection capabilities ranged between 10.61 to 12.12 μ</span><span lang="&quot;EN-US&quot;">g/kg and 11.22 to 14.25 μ<span lang="&quot;EN-US&quot;">g/kg, respectively.</span></span>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2016-01-15 08:54:03
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/7702
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 6, ##issue.no## 4 (2015): December 2015
 
Language Note en
 
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