<p><span>Evaluation of antimicrobial activity of chemical constituents of </span><em>Achyranthes aspera</em><span> L. roots against human pathogens</span></p>
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Title Statement |
<p><span>Evaluation of antimicrobial activity of chemical constituents of </span><em>Achyranthes aspera</em><span> L. roots against human pathogens</span></p> |
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Added Entry - Uncontrolled Name |
Owk, Aniel Kumar; andhra university Mortha, Krishna Rao Lagudu, Mutyala Naidu UGC-SERO, Hyderabad |
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Uncontrolled Index Term |
Achyranthes aspera, Alcohol extract, Antimicrobial activity, MIC, Human pathogenic bacteria. |
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Summary, etc. |
<p><span>Antimicrobial activity of roots of </span><em>Achyranthes aspera</em><span> L. (Family-Amaranthaceae) was studied against seven pathogenic bacterial and three fungal strains by agar well diffusion method. Antimicrobial activity was recorded for hexane, chloroform, methanol, ethanol and aqueous extracts. Alcohol (ethanol and methanol) extracts exhibited higher degree of antimicrobial activity compared to aqueous, chloroform and hexane extracts. </span><em>Klebsiella pneumoniae</em><span> turned out to be the most susceptible bacterium to the crude chemical constituents of roots using the standard drugs, Tetracycline and Clotrimazole. Minimum inhibition concentration values of chloroform, methanol, ethanol and aqueous extracts were determined by the agar dilution method ranged between 62.5 and 1000 µg. The study suggests that the root extracts possess bioactive compounds with antimicrobial activity against the tested bacteria and fungi revealing a significant scope to develop a novel broad spectrum antimicrobial drug formulation from </span><em>A. aspera</em><span>.</span></p> |
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Publication, Distribution, Etc. |
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] 2016-02-19 08:35:30 |
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Electronic Location and Access |
"application/pdf" http://op.niscair.res.in/index.php/IJNPR/article/view/4699 |
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Data Source Entry |
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 5, ##issue.no## 3 (2014): September 2014 |
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Language Note |
en |
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Nonspecific Relationship Entry |
http://op.niscair.res.in/index.php/IJNPR/article/download/4699/10280 |
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Terms Governing Use and Reproduction Note |
Except where otherwise noted, the Articles on this site are licensed underCreative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India© 2012. The Council of Scientific & Industrial Research, New Delhi. |
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