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Preparation of ultra-porous UPM/PHBV nanofibres using solvent-etching technology and drug-loading efficiency

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Title Statement Preparation of ultra-porous UPM/PHBV nanofibres using solvent-etching technology and drug-loading efficiency
 
Added Entry - Uncontrolled Name Jin, Lanming ; Jiangnan University
Jiang, Gaoming ; Jiangnan University
Liu, Shuiping ; Jiangnan University
 
Uncontrolled Index Term Drug loading efficiency; Electrospinning; Poly(3-hydroxybutyrateco-3-hydroxyvalerate); Solvent etching; Ultra-porous fibres; Nanofibres; Unsaturated polyester macromonomers
 
Summary, etc. <p class="Abstract" style="text-align: justify;">In this study, ultra-porous fibres have been produced by partly washing out poly(3-hydroxybutyrateco-3-hydroxyvalerate) (PHBV) from the heat-crosslinked electrospun unsaturated polyester macromonomers/poly(3-hydroxybutyrateco-3-hydroxyvalerate) (UPM/PHBV) fibrous composite using chloroform. Tetracycline hydrochloride has been used as the module drug to test the drug-loading efficiency of porous fibres. Field emission scanning electron microscope images show that the etched UPM/PHBV fibres have lost the original smooth surface. The result demonstrates that the PHBV is successfully washed by chloroform, but most of UPM is remained because of the heat-crosslinking. Furthermore, with the increase of PHBV ratio in composite fibres, the etched fibres show much rougher surface. The drug absorption behavior also varies with the different PHBV ratios.</p>
 
Publication, Distribution, Etc. Indian Journal of Fibre & Textile Research (IJFTR)
2015-01-09 11:10:04
 
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http://op.niscair.res.in/index.php/IJFTR/article/view/3334
 
Data Source Entry Indian Journal of Fibre & Textile Research (IJFTR); ##issue.vol## 39, ##issue.no## 4 (2014): Indian Journal of Fibre & Textile Research
 
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