Studies On Rabies Diagnosis, Prevalence And Factors Affecting Immune Response To Vaccination
KrishiKosh
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Title |
Studies On Rabies Diagnosis, Prevalence And Factors Affecting Immune Response To Vaccination
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Creator |
Yale, Gowri
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Contributor |
Ganesan, P.I.
Thangavelu, A. Tirumurugaan, K.G. Vijaya Bharathi, M. |
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Subject |
Antibody level
Direct Rapid Immunohistochemistry test Fluorescent Antibody test Immunity Prevalence Rabies Rapid Fluorescentce Focus Inhibition test Skin Vaccine |
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Description |
This study concentrates on the factors affecting immune response to rabies vaccination in dogs, prevalence and determinants of dog rabies in Chennai and to evaluate the suitability of nuchal skin biopsy as an alternate sample for rabies diagnosis. Many factors play a role in immunity and maintenance of protective antibody levels of vaccination. This study shows that regular vaccination, regular exercise, companionship, non descript breed,neutering, age above 1 year with annual booster dose favored long duration of immunity in the dog. An epidemiological study of rabies cases reported in Madras Veterinary College from January 2010 to December 2012 showed that 204 animals were suspected for rabies of which 181 were dogs; of which 148 werepositive. Seasonal pattern,age, breed and sex predilection were observed. This study shows that north Chennai reported more dog bites in humans and rabies in dogs; this could be due to a higher dog population in this region. Educational qualification of the people did not help people from avoiding a dog bite, speed consultation seeking or vaccinating their dogs against rabies. This study evaluated the suitability of nuchal skin biopsy as an alternate sample for diagnosis of rabies using Modified Direct Rapid Immunohistochemistry test. The sensitivity and specificity of DRIT and modified DRIT using skin has shown that nuchal skin can be used as an alternative sample for rabies diagnosis especially in cases where the brain is not fit for diagnosis. |
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Date |
2016-05-24T12:02:10Z
2016-05-24T12:02:10Z 2013 |
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Type |
Thesis
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Identifier |
http://krishikosh.egranth.ac.in/handle/1/66266
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Language |
en
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Format |
application/pdf
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Publisher |
Tamil Nadu Veterinary and Animal Sciences University
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