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Prostaglandin F2α (Cloprostenol) in Treatment of Open Cervix Pyometra in Bitches

KrishiKosh

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Title Prostaglandin F2α (Cloprostenol) in Treatment of Open Cervix Pyometra in Bitches
 
Creator Thirumurugan, K.
Rajasundaram, R.C.
 
Description Eighteen bitches of different breeds that were presented to the Small Animal Obstetrics and Gynaecology Unit, Madras Veterinary College Teaching Hospital, with known breeding history of open cervix pyometra, were formed as experimental animal for the study. These bitches were randomly divided into three groups (n=6) viz. group I, II and III.
Diagnosis of open cervix pyometra was made based on history, clinical signs, abdominal palpation, ultrasonography and radiography. Group I bitches were treated with Inj. Prostaglandin F2α (Cloprostenol) at the dose rate of 5µ g/kg body weight subcutaneously once daily, Group II bitches were treated with Inj. Aglepristone at the dose rate of 10mg/kg body weight subcutaneously on day 1, day 2, day 7 and day 14 (if not cured), Group III bitches were treated with Inj. Aglepristone plus Prostaglandin F2α Inj. Aglepristone @ 10mg/kg and Inj. PGF2α @ 1 µ g/kg body weight subcutaneously on day 1, day , day 7 and day 14 (if not cured), respectively and Inj. PGF2α alone was administered @ 2 µ g/kg body weight subcutaneously on day 3 to day 6. All the three groups were treated along with antibiotics and fluids, until the uterine size was reduced or no visible intrauterine fluid or anechoic to hypoechoic area seen. All the three
treatment protocols (PGF2α aglepristone and aglepristone plus PGF2α combination) were 100 per cent effective in open cervix pyometra of bitches and can be adopted as a remedial measure under field condition to augment fertility in bitches. Further, the drug aglepristone treatment was found to be better, since it requires minimum number of administration of the drug without any side effect.
 
Date 2016-06-22T14:43:15Z
2016-06-22T14:43:15Z
2011-12
 
Type Article
 
Identifier http://krishikosh.egranth.ac.in/handle/1/67727
 
Language en
 
Format application/pdf
 
Publisher Journal of Indian Veterinary Association, Kerala