Molecular Characterization of Mineral Phosphate Solubilization In Serratia marcescens AND Methylobacterium sp.
KrishiKosh
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Title |
Molecular Characterization of Mineral Phosphate Solubilization In Serratia marcescens AND Methylobacterium sp.
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Creator |
Archana Kumari
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Contributor |
P.U. Krishnaraj
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Subject |
Plant Biotechnology
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Description |
The major goal of the present investigation was to study the mechanism of mineral phosphate solubilization in Serratia marcescens and Methylobacterium sp. All the 157 isolates of S. marcesens and 73 isolates of pink pigmented facultative methylotrophs were screened for their mineral phosphate solubilization phenotype on solid media viz., Modified Sperber’s and TCP agar media. Eight most potent isolates along with one reference strain Serratia marcescens ER2 were further screened for pH drop and Pi release in NBRIP-BPB and TCP broth. Both pH drops and Pi release were highly correlated upto 15 days. AUDS-151 and PPFM87 were the most potent ‘P’ solubilizing isolates. Gluconic acid was detected in the culture supernatants of these isolates through thin layer chromatographic technique. Effect of buffering and phosphate stress on MPS phenotype of these isolates were observed by external supply of tris buffer and K2HPO4 to the MSM agar medium. It indicates the metabolic control of mineral phosphate solubilization by external factors which either resist the change in pH or alters the gene expression. Tn5 mutants were generated from the most potent P solubilizing isolate AUDS-151 by biological (Tn5) mutagenesis. Mutants failed to show MPS activity even after 5 DAI. Strainal identity of AUDS-151 and PPFM-87 was confirmed as S. marcescens and Methylobacterium mesophilicum respectively through 16S rDNA sequencing. All the pqq operon gene (s) were amplified from AUDS-151 and PPFM-87 and the most conserved pqqE gene was cloned into E. coli DH5a from both the isolates. Both the clones pAMK101 and pASK101 were sequenced and showed 97 per cent homology with the Methylobacterium sp. (CPOOOO367) and 94 per cent homology with Serratia marcescens (DQ868536), respectively. |
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Date |
2016-11-12T13:07:50Z
2016-11-12T13:07:50Z 2011 |
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Type |
Thesis
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Identifier |
http://krishikosh.egranth.ac.in/handle/1/85217
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Format |
application/pdf
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Publisher |
UAS, Dharwad
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