MOLECULAR ANALYSIS OF TRANSGENIC GROUNDNUT FOR DROUGHT TOLERANCE GENES
KrishiKosh
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Title |
MOLECULAR ANALYSIS OF TRANSGENIC GROUNDNUT FOR DROUGHT TOLERANCE GENES
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Creator |
NEELIMA, S
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Contributor |
MANORAMA, K
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Subject |
MOLECULAR, ANALYSIS, TRANSGENIC, GROUNDNUT, DROUGHT, TOLERANCE, GENES
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Description |
Groundnut (Arachis hypogaea L.) is an important legume cash crop whose crop productivity and yield stability are affected by abiotic stresses such as drought. Drought is a complex phenomenon. Research in transgenic crops may offer new means to improve agriculture particularly in dry areas, as genes specifically involved in response to drought have been identified (Lieu et al., 2000). However, a major challenge of transgenic research besides obtaining transgenic material is to understand the responses of plants to their external environment and identify new targets for improving stress tolerance. Transgenic groundnut plants (rd29A: DREB1A) tolerant to drought, were initially evaluated for the expression of npt II and DREB 1 A genes through PCR and RT-PCR. The plants positive for npt II gene were subjected to water stress conditions using a typical dry-down procedure (Ritchie 1980; Sinclair and Ludlow, 1986; Ray and Sinclair, 1997) in P2 level containment greenhouse. To understand the molecular mechanism and differential gene expression under water stress conditions, a highly sensitive technique namely DDRT-PCR (Differential display Reverse transcription-Polymerase chain reaction), which facilitates identification and isolation of differentially expressed genes, has been employed in the present study. Differential display studies were carried out using 20 RT-PCR positive plants for DREB 1A gene. Twenty drought stress-responsive partial cDNAs were initially identified by comparing expression profiles between water stressed transgenic and non-transgenic plants by means of differential display. Among these 9 were newly expressed (induced), 5 were up-regulated and 6 were down-regulated. Interestingly, the sequence analysis of 8 differentially expressed clones identified that the EST function of 4 cDNA clones was similar to that of stress related genes. Two were similar to that of cold stress, one to that of water stress and one to abiotic stress. The function of the remaining four clones was not known. This indicates that many of the abiotic stress responsive pathways may be interlinked. For the clones identified to be differentially expressed in response to drought, their stress-regulated expression and function needs to be confirmed and investigated further. The transcripts identified in this study also have great potential as molecular markers. |
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Date |
2016-08-22T13:01:56Z
2016-08-22T13:01:56Z 2005 |
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Type |
Thesis
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Identifier |
http://krishikosh.egranth.ac.in/handle/1/73273
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Language |
en
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Relation |
D7514;
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Format |
application/pdf
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Publisher |
ACHARYA N.G. RANGA AGRICULTURAL UNIVERSITY, RAJENDRANAGAR, HYDERABAD
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