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DIAGNOSTIC AND THERAPEUTIC STUDIES ON RECURRENT PYODERMA IN DOGS

KrishiKosh

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Title DIAGNOSTIC AND THERAPEUTIC STUDIES ON RECURRENT PYODERMA IN DOGS
MVSC;CVSc;TPTY; Acc No:T1360
 
Creator SUDHAKARA REDDY, B
 
Contributor NALINI KUMARI, K (Major)
VAIKUNTA RAO, V
CHENGALVA RAYULU, V
 
Subject DOGS; PYODERMA; THERAPEUTIC STUDIES
 
Description THESES
ABSTRACT :
The present study was undertaken to study the etiology, make an attempt to identify the underlying factors and to assess the efficacy of different therapeutic agents in recurrent pyoderma in dogs.
The highest occurrence of recurrent pyoderma from among the cases undertaken for study was noticed in Labrador and non-descript dogs. Maximum number of cases was from the age group of 3-5 years. Occurrence was more common in females than male dogs. Recurrent superficial pyoderma (76%) was more common than recurrent deep pyoderma (24%). The major locations of lesions for recurrent superficial pyoderma included lateral abdomen, lateral thorax and dorsum, axilla, groin, hind limb, foot, neck and fore limb and head. Clinical examination of dogs with recurrent superficial pyoderma revealed symptoms such as papules, pustules and crusted papules. Secondary lesions such as erythema, alopecia, crusts, scales, plaques and epidermal collarettes were also observed. Pruritus was observed in all the cases. In dogs affected with recurrent deep pyoderma, symptoms like papules, pustules, cellulitis, ulcers, crusted papules, nodules, fistulous tracts, alopecia, scale formation, crusts, hyper pigmentation, erosions and furunculosis, pain and edema were recorded.
Haemotology and serum biochemical evaluation revealed leucocytosis (13032.80±50.16/cumm), increase in absolute neutrophil (10417 ±525.72 /cumm) and eosinophil count (496.54±50.15/cumm) and cholesterol (179.32 ±22.14 mg/dl). Affected dogs also had decreased haemoglobin (11.49 ±0.30 g/dl) and TEC (5.85 ±0.14 x 106/cumm). Decreased total T4 (1.35 μg/dL to 1.85 μg/dL) and free T4 (0.6 ng/dL to 0.75ng/dL) levels in three dogs were suggestive of hypothyroidism out of 25 dogs examined with recurrent pyoderma.
Cultural examination revealed Staphylococci in all the dogs, of which 6 were of Staphylococcus aureus (24%), fifteen, Staphylococcus intermedius (60%) and four were suggestive of Staphylococcus schleiferi (16%). Thirteen cases had other bacteria like Streptococci (16%), Klebsiella (16%), Escherichia coli (12%) and Pseudomonas (8%) along with Staphylococci.
Wide variety of associated conditions / underlying factors could be detected in recurrent pyoderma, but with the involvement of ectoparasitic infections in higher propensity (52%).
Antibiotic sensitivity test of whole cultures as well as individual organisms revealed high susceptibility to cefpodoxime with clavulanic acid, ciprofloxacin and amoxicillin with sulbactum, enrofloxacin, chloramphenicol, cephadroxil and amikacin. The isolates were found to be resistant to tylosin, amoxicillin with clavulanic acid, lincomycin, erythromycin, azithromycin, cephalexin and co-trimoxazole.
Therapy was carried out with two antibiotics viz. cefpodoxime with clavulanic acid (Group-1) and enrofloxacin (Group-2) along with similar adjunctive therapy besides addressing the probable underlying causes appropriately. Efficacy of the both drugs @ 5mg/kg body weight, orally, once daily, was found to be 100 per cent. Hence, it was concluded that both the antibiotics were efficacious in the treatment of recurrent pyoderma in dogs without any adverse effects. However, comparatively early recovery was seen with cefpodoxime with clavulanic acid though costlier than enrofloxacin.
Reintroduction of allergic food and laboratory confirmation of hypothyroidism after completion of therapy could be responsible for the recurrence (10 %, in each group) noticed during the three month observatory period.
DEPARTMENT OF VETERINARY CLINICAL MEDICINE, ETHICS AND JURISPRUDENCE
SRI VENKATESWRA VETERINARY UNIVERSITY
COLLEGE OF VETERINARY SCIENCE
TIRUPATI – 517 502 (A.P.) INDIA
 
Date 2016-12-27T12:25:17Z
2016-12-27T12:25:17Z
2010-08
 
Type Thesis
 
Identifier http://krishikosh.egranth.ac.in/handle/1/93178
 
Language en
 
Format application/pdf
 
Publisher Sri Venkateswara Veterinary University, TIRUPATI – 517 502,A.P