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A Preliminary Study on the Anti Neoplastic Effect of Prodigiosin Produced by Serratia marcescens Isolated from Termite (Odontotermes formosanus)

KrishiKosh

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Title A Preliminary Study on the Anti Neoplastic Effect of Prodigiosin Produced by Serratia marcescens Isolated from Termite (Odontotermes formosanus)
Indian J. Vet. Pathol., 37(2) : 195-198
 
Creator Vijayarani, K.
Gowralkar, Maheswarappa
Sesh, P.S.L.
Savithri, M.
Kumanan, K.
 
Subject Antineoplastic
Prodigiosin
Serratia marcescens
Termite
 
Description Prodigiosin, a natural red pigment produced by a variety of bacteria has been reported to have antibacterial, antifungal, anti malarial and anti neoplastic activity. In this study, prodigiosin produced by Serratia marcescens has been tested for its in vitro anti neoplastic activity. S.marcescens was isolated from termite gut, identified and characterized by morphology, Gram’s staining, biochemical and carbohydrate
fermentation tests. S. marcescens produced red to dark pigment on nutrient agar. Prodigiosin produced by S. marcescens was purified by thin layer chromatography. The antineoplastic effect of the pigment was assessed in cancerous cell lines such as HeLa and HEp2 by MTT assay and Comet assay. Cytotoxic properties of prodigiosin pigment was evaluated by using Vero cells.
 
Date 2016-06-28T12:46:37Z
2016-06-28T12:46:37Z
2013
 
Type Article
 
Identifier http://krishikosh.egranth.ac.in/handle/1/68131
 
Language en
 
Format application/pdf
 
Publisher Indian Journal of Veterinary Pathology