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Assessment of insecticides risk posed to infants due to mothers’ milk and branded formulae

KrishiKosh

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Title Assessment of insecticides risk posed to infants due to mothers’ milk and branded formulae
 
Creator Neeta Devi
 
Contributor Sharma, I.D.
 
Subject organochlorine compounds, sampling, animal husbandry, insecticides, pesticides, land management, fruits, inorganic acid salts, concentrates, prepared foods
 
Description The present piece of research entitled “Assessment of insecticides risk posed to infants due to
mothers’ milk and branded formulae” was undertaken to know the status of insecticide residues in
mothers’ milk and infant formulae. Overall 153 mothers’ milk samples were monitored in four
different agroclimatic zones of Himachal Pradesh covering all the twelve districts of the state. The
QuEChERS method proved cheapest and less time consuming with 90-120% recovery, among all the
methods performed (MRM I, MRM II and The QuEChERS). The LOD and LOQ of nineteen studied
insecticides ranged between 0.001 to 0.010 and 0.005 to 0.040 mg kg-1, respectively. The p, p’-DDE
was the major contaminant found in 26.80% samples followed by p,p’-DDT (1.30%) and chlorpyrifos
(0.65%). However, residues of other insecticides included in this study were below determination limit
(BDL). Mean DDT levels in mothers’ milk were 0.240 mg kg-1 fat (0.011 mg kg-1 milk), 0.171 mg kg-1
fat (0.010 mg kg-1 milk), 0.026 mg kg-1 fat (0.001 mg kg-1 milk) and below detectable limit (BDL) in
Zones I, II, III and IV, respectively. Insecticide residues were not found in mothers residing in
industrial area and in branded infant formulae. The mothers’ environment, parity or length of previous
lactations, age, weight, diet, occupation and mobilization of fat were identified as the most important
factors affecting the transfer of insecticide residues into mothers’ milk. The residue levels were
determined to decrease with an increase in parity and infants’ weight and to increase with the age,
weight and height of the mothers. The determination of a low DDT/DDE ratio (0.050) indicated past
exposure of mothers to DDT from the environment. The estimated daily exposure of neonates to -
DDT was determined to be considerably lower (0.001 mg kg-1 bodyweight) than the ADI (0.02 mg kg-1
bodyweight) indicating no appreciable risk to one-month-old infants. The trend comparison with past
studies conducted around the world indicate a decline in the levels of organochlorine insecticide
residues in mothers' milk and further drop of ADI in infants. Considering the low health risk to the
infants and the associated benefits of breast feeding to mothers and their neonates, mothers should not
discontinue breastfeeding. The study advocates a constant bio-monitoring of lactating mothers’ milk
for insecticide residues to minimize the health risks to infants and thereby to the future generation.
 
Date 2016-04-28T14:05:43Z
2016-04-28T14:05:43Z
2015
 
Type Thesis
 
Identifier http://krishikosh.egranth.ac.in/handle/1/65639
 
Language en
 
Format application/pdf
 
Publisher YSPU