Record Details

A facile approach towards enantiomerically pure masked β-amino alcohols

IR@CSIR-IIIM

View Archive Info
 
 
Field Value
 
Title A facile approach towards enantiomerically pure masked β-amino alcohols
 
Creator Gupta, Pankaj
Shah, Bhahwal Ali
Parshad, Rajinder
Qazi, Ghulam Nabi
Taneja, Subhash Chandra
 
Subject Chemical Sciences
 
Description b-Amino alcohols are bioactive molecules, used also as catalysts in asymmetric C–C bond formation. While asymmetric synthesis has been the preferred route for their preparation, there was always been a need to develop a facile methodology involving environmentally friendly transformations. Masked amines in the form of phthalimide alcohols, prepared via a fast coupling reaction in an ionic liquid as a reusable reaction media together with reduction and an efficient biocatalytic resolution, offer a green methodology for enantiomerically pure products(ee . 99%, 50 g L21).
 
Date 2007
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/186/1/10.1039b701192j.pdf
Gupta, Pankaj and Shah, Bhahwal Ali and Parshad, Rajinder and Qazi, Ghulam Nabi and Taneja, Subhash Chandra (2007) A facile approach towards enantiomerically pure masked β-amino alcohols. Green Chemistry, 9 (10). p. 1120. ISSN 1463-9262
 
Relation http://dx.doi.org/10.1039/b701192j
http://iiim.csircentral.net/186/