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Micro-LC Determination of Swertiamarin in Swertia species and Bacoside-A in Bacopa monnieri

IR@CSIR-IHBT

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Title Micro-LC Determination of Swertiamarin
in Swertia species and Bacoside-A
in Bacopa monnieri
 
Creator Bhandari, P
Kumar, Neeraj
Singh , Bikram
Gupta, A P
Kaul, V K
 
Subject Natural Product Chemistry
 
Description A microanalytical HPLC technique has been developed for determination of swertiamarin in
Swertia species and bacoside-A in Bacopa monnieri. Small quantities (‡2 mg) of powdered
plant material are required for analysis. The limits of detection (LOD) of swertiamarin and
bacoside-A are 500 pg and 4,000 ng, respectively, in 2 mg plant material. Dried plant
material from S. cordata and S. chirata contained 5.59 and 0.44% swertiamarin, respectively,
and B. monnieri contained 0.12% bacoside-A. The simplicity, accuracy, and reproducibility of
the method enable its use for estimation of marker compounds.
 
Publisher VIEWEG, Abraham-Lincoln-Strabe 46, Postfach 15 47, D-65005 Wiesbaden, Germany
 
Date 2006
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://ihbt.csircentral.net/50/1/2006_Micro-LC.pdf
Bhandari, P and Kumar, Neeraj and Singh , Bikram and Gupta, A P and Kaul, V K (2006) Micro-LC Determination of Swertiamarin in Swertia species and Bacoside-A in Bacopa monnieri. Chromatographia, 64 (9-10). pp. 599-602. ISSN 0009-5893
 
Relation http://ihbt.csircentral.net/50/