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Anti-anaphylactic effect of Euphorbia hirta

IR@CSIR-IIIM

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Title Anti-anaphylactic effect of Euphorbia hirta
 
Creator YOUSSOUF, M
KAISER, P
TAHIR, M
SINGH, G
SINGH, S
SHARMA, V
SATTI, N
HAQUE, S
JOHRI, R
 
Subject Pharmacological Sciences
 
Description The Euphorbia hirta ethanolic extract (EH A001) was found to possess a prominent anti-anaphylactic activity. A preventive
effect of EH-A001 given by oral route at dose from 100 to 1000 mg/kg was observed against compound 48/80-induced systemic anaphylaxis. At the same range of dose, EH-A001 inhibited passive cutaneous anaphylaxis (PCA) in rat and active paw anaphylaxis in mice. A suppressive effect of EH-A001 was observed on the release of TNF-α and IL-6 from anti-DNP-HSA activated rat peritoneal mast cells.
 
Date 2007
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/209/1/10.1016j.fitote.2007.06.003.pdf
YOUSSOUF, M and KAISER, P and TAHIR, M and SINGH, G and SINGH, S and SHARMA, V and SATTI, N and HAQUE, S and JOHRI, R (2007) Anti-anaphylactic effect of Euphorbia hirta. Fitoterapia, 78 (7-8). pp. 535-539. ISSN 0367326X
 
Relation http://dx.doi.org/10.1016/j.fitote.2007.06.003
http://iiim.csircentral.net/209/