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Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli

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Title Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli
 
Creator Bani, Sarang
Kaul, Anpurna
Khan, Beenish
Gupta, Vijay Kumar
Satti, Naresh Kumar
Suri, Krishan Avtar
Qazi, Ghulam Nabi
 
Subject Pharmacological Sciences
 
Description The present study was undertaken to investigate the anti-arthritic activity of a biopolymeric fraction (BET) from plant Euphorbia tirucalli Boiss (Euphorbiaceae). The fraction showed dose dependent anti-arthritic activity and also showed in vivo immunomodulatory capacity being
a major component in inhibiting arthritis. It caused suppression of CD4+ and CD8+ T cells, inhibition of intracellular Interleukin-2 (IL-2) and Interferon-gamma (IFN-�) by flowcytometry. It inhibited vascular permeability and the migration of leucocytes at the site of the insult. The oral LD0 in both rats and mice was more than 2000 mg/kg.
 
Date 2007
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/210/1/10.1016j.jep.2006.09.021.pdf
Bani, Sarang and Kaul, Anpurna and Khan, Beenish and Gupta, Vijay Kumar and Satti, Naresh Kumar and Suri, Krishan Avtar and Qazi, Ghulam Nabi (2007) Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli. Journal of Ethnopharmacology, 110 (1). pp. 92-98. ISSN 03788741
 
Relation http://dx.doi.org/10.1016/j.jep.2006.09.021
http://iiim.csircentral.net/210/