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Enantiomerically pure α-methoxyaryl acetaldehydes as versatile precursors: a facile chemo-enzymatic methodology for their preparation

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Title Enantiomerically pure α-methoxyaryl acetaldehydes as versatile precursors: a facile chemo-enzymatic methodology for their preparation
 
Creator Singh, Buddh
Gupta, Pankaj
Chaubey, Asha
Parshad, Rajinder
Sharma, Shiromani
Taneja, Subhash C.
 
Subject Chemical Sciences
 
Description A facile and efficient synthesis of optically active a-methoxyaryl acetic acids (up to 95% ee), a-methoxyaryl
ethanols (up to 93% ee) and a-methoxyaryl acetonitriles (up to 93% ee) was achieved via Arthrobacter sp. lipase-catalyzed kinetic resolution of masked aldehydes as the key synthons, that is, a-hydroxyaryl
acetaldehyde acetals.
 
Date 2008
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/248/1/10.1016j.tetasy.2008.10.023.pdf
Singh, Buddh and Gupta, Pankaj and Chaubey, Asha and Parshad, Rajinder and Sharma, Shiromani and Taneja, Subhash C. (2008) Enantiomerically pure α-methoxyaryl acetaldehydes as versatile precursors: a facile chemo-enzymatic methodology for their preparation. Tetrahedron: Asymmetry, 19 (22). pp. 2579-2588. ISSN 09574166
 
Relation http://dx.doi.org/10.1016/j.tetasy.2008.10.023
http://iiim.csircentral.net/248/