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Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential

IR@CSIR-IIIM

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Field Value
 
Title Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential
 
Creator Shah, Bhahwal Ali
Chib, Renu
Anand, Naveen
Pandey, Anjali
Kapoor, Kamini
Bani, Sarang
Gupta, Vivek K.
K, Rajnikant
Sethi, Vijay K.
Taneja, Subhash Chandra
 
Subject Chemical Sciences
 
Description Naturally occurring acetylated pseudoguaianolides and psilostachyin including their analogues were synthesized.
The structure of semi-synthetic psilostachyin was also confirmed by X-ray crystallography. The anti-inflammatory potential of all the derivatives has been evaluated through in vitro expression of TNF-a, IL-1b and IL-6 in murine neutrophils.
 
Date 2011
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/320/1/10.1016j.bmcl.2011.06.037.pdf
Shah, Bhahwal Ali and Chib, Renu and Anand, Naveen and Pandey, Anjali and Kapoor, Kamini and Bani, Sarang and Gupta, Vivek K. and K, Rajnikant and Sethi, Vijay K. and Taneja, Subhash Chandra (2011) Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential. Bioorganic & Medicinal Chemistry Letters, 21 (16). pp. 4847-4851. ISSN 0960894X
 
Relation http://dx.doi.org/10.1016/j.bmcl.2011.06.037
http://iiim.csircentral.net/320/