Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines
IR@CSIR-IIIM
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Title |
Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines
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Creator |
Naqvi, Tahira
Mahajan, Deepali Sharma, Rattan Lal Khan, Inshad Ali Kapoor, Kamal K. |
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Subject |
Chemical Sciences
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Description |
A series of novel 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,50-isoxazoline-2}-30-yl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepines were synthesized. These molecules were screened in vitro for their antifungal and antibacterial activity, and none of the tested compounds showed promising antimicrobial or antifungal activity.
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Date |
2010
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://iiim.csircentral.net/351/1/10.1002jhet.194.pdf
Naqvi, Tahira and Mahajan, Deepali and Sharma, Rattan Lal and Khan, Inshad Ali and Kapoor, Kamal K. (2010) Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines. Journal of Heterocyclic Chemistry, 48 (1). pp. 144-148. ISSN 0022152X |
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Relation |
http://dx.doi.org/10.1002/jhet.194
http://iiim.csircentral.net/351/ |
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