ICAR Research Data Repository for Knowledge Management
Synthesis and cytotoxic activity of some novel polycyclic γ-butyrolactones
IR@CSIR-IIIM
View Archive Info| Field | Value | |
| Title |
Synthesis and cytotoxic activity of some novel polycyclic γ-butyrolactones
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| Creator |
Ishar, M.P.S.
Raj, Tilak Agrawal, Satyam Kumar Saxena, A.K. Singh, Lakhwinder Singh, Rajinder Bhella, Surinderjit Singh |
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| Subject |
Chemical Sciences
Pharmacological Sciences |
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| Description |
Baeyer–Villiger oxidation of 5-aryl-7,11,11-trimethyltricyclo[5.4.0.03,6]-undec-1-en-4-ones 4a–h by H2O2 and formic acid in methanol yields mixtures of 3b,7,7-trimethyl-3-phenyl-3,3a,3b,4,5,6,7,8a-octahydro- 1H-indeno-[1,2-c]furan-1-ones 8a–h and 3b,7,7-trimethyl-3-phenyl-3,3a,3b,4,5,6,7,8a-octahydro-1H-indeno-[1,2-c]furan-2-ones 9a–h in high yields. The obtained butyrolactones 8a–h display cytotoxic activity against a number of human cancer cells. |
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| Date |
2008
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/353/1/10.1016j.bmcl.2008.07.095.pdf
Ishar, M.P.S. and Raj, Tilak and Agrawal, Satyam Kumar and Saxena, A.K. and Singh, Lakhwinder and Singh, Rajinder and Bhella, Surinderjit Singh (2008) Synthesis and cytotoxic activity of some novel polycyclic γ-butyrolactones. Bioorganic & Medicinal Chemistry Letters, 18 (17). pp. 4809-4812. ISSN 0960894X |
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| Relation |
http://dx.doi.org/10.1016/j.bmcl.2008.07.095
http://iiim.csircentral.net/353/ |
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