ICAR Research Data Repository for Knowledge Management
Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus
IR@CSIR-IIIM
View Archive Info| Field | Value | |
| Title |
Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus
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| Creator |
Khan, I. A.
Mirza, Z. M. Kumar, A. Verma, V. Qazi, G. N. |
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| Subject |
Pharmacological Sciences
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| Description |
Piperine, a trans-trans isomer of 1-piperoyl-piperidine, in combination with ciprofloxacin markedly reduced the MICs and mutation prevention concentration of ciprofloxacin for Staphylococcus aureus, including methicillin-resistant S. aureus. The enhanced accumulation and decreased efflux of ethidium bromide in the wild-type and mutant (CIPr-1) strains in the presence of piperine suggest its involvement in the inhibition of bacterial efflux pumps. |
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| Date |
2006
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/379/1/10.1128AAC.50.2.810%E2%80%93812.2006.pdf
Khan, I. A. and Mirza, Z. M. and Kumar, A. and Verma, V. and Qazi, G. N. (2006) Piperine, a Phytochemical Potentiator of Ciprofloxacin against Staphylococcus aureus. Antimicrobial Agents and Chemotherapy, 50 (2). pp. 810-812. ISSN 0066-4804 |
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| Relation |
http://dx.doi.org/10.1128/AAC.50.2.810-812.2006
http://iiim.csircentral.net/379/ |
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