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Role of extracytoplasmic leucine rich repeat proteins in plant defence mechanisms

IR@CSIR-IHBT

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Title Role of extracytoplasmic leucine rich repeat
proteins in plant defence mechanisms
 
Creator Shanmugam, V
 
Subject Microbiology
 
Description Plant–pathogen interactions involve highly complex series of reactions in disease
development. Plants are endowed with both, resistance and defence genes. The
activation of defence genes after contact with avirulence gene products of pathogens
depends on signals transduced by leucine-rich repeats (LRRs) contained in resistance
genes. Additionally, LRRs play roles for various actions following ligand recognition.
Polygalacturonase inhibiting proteins (PGIPs), the only plant LRR protein with known
ligands, are pectinase inhibitors, bound by ionic interactions to the extracellular
matrix (ECM) of plant cells. They have a high affinity for fungal endopolygalacturonases
(endoPGs). PGIP genes are organised in families encoding proteins with similar
physical characteristics but different specificities. They are induced by infection and
stress related signals. The molecular basis of PG–PGIP interaction serves as a model to
understand the evolution of plant LRR proteins in recognising non-self-molecules.
Extensins form a different class of structural proteins with repetitive sequences. They
are also regulated by wounding and pathogen infection. Linkage of extensins with LRR
motifs is highly significant in defending host tissues against pathogen invasion.
Overexpression of PGIPs or expression of several PGIPs in a plant tissue, and perhaps
manipulation of extensin expression could be possible strategies for disease management.
& 2004 Elsevier GmbH. All rights reserved.
 
Date 2005
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://ihbt.csircentral.net/387/1/128_2005_Role_of.pdf
Shanmugam, V (2005) Role of extracytoplasmic leucine rich repeat proteins in plant defence mechanisms. Microbiological Research, 160. pp. 83-94.
 
Relation http://ihbt.csircentral.net/387/