Record Details

Umbelliferone – An antioxidant isolated from Acacia nilotica (L.) Willd. Ex. Del.

IR@CSIR-IHBT

View Archive Info
 
 
Field Value
 
Title Umbelliferone – An antioxidant isolated from Acacia nilotica (L.) Willd. Ex. Del.
 
Creator Singh, R
Singh , Bikram
Singh, S
Kumar, Neeraj
Kumar, Sanjay
Arora, S
 
Subject Plant Biotechnology
Natural Product Chemistry
 
Description The bark and leaves of Acacia nilotica are consumed for their promising medicinal properties in several parts of the world. The aerial portion, including flowers, is used as fodder for animals. This study aimed to isolate the functional components of A. nilotica and to check their antioxidant activities in vitro. In the fractionation of methanol extract, a fraction, AN-2, was isolated, which was identified by spectroscopic techniques, namely NMR and mass spectroscopy to be a coumarin derivative, i.e. umbelliferone. The antioxidative activities, including the DPPH , deoxyribose (site and non-site specific), chelating power, reducing power and lipid peroxidation assays, were studied in vitro and performed in the Dept. of Botanical and Env. Sciences, GNDU, Amritsar. It was found that the antioxidative effect of umbelliferone was dose-dependent up to 100 μg/ml and then levelled off with no further increase in activity. This is the first report of the isolation and antioxidant potential of umbelliferone from A. nilotica.
 
Date 2010
 
Type Article
PeerReviewed
 
Identifier Singh, R and Singh , Bikram and Singh, S and Kumar, Neeraj and Kumar, Sanjay and Arora, S (2010) Umbelliferone – An antioxidant isolated from Acacia nilotica (L.) Willd. Ex. Del. Food Chemistry, 120 (3). pp. 825-830.
 
Relation http://ihbt.csircentral.net/639/