ICAR Research Data Repository for Knowledge Management
A Rapid and Efficient Microwave-Assisted Synthesis of Substituted 3-Phenylpropionic Acids from Benzaldehydes in Minutes.
IR@CSIR-IHBT
View Archive Info| Field | Value | |
| Title |
A Rapid and Efficient Microwave-Assisted Synthesis of Substituted 3-Phenylpropionic Acids from Benzaldehydes in Minutes.
|
|
| Creator |
Sharma , A
Joshi, B P Sinha, Arun K |
|
| Subject |
Nanotechnology
|
|
| Description |
A convenient, inexpensive, and efficient synthesis of 3-phenylpropionic acids (1a–1f) by reacting benzaldehyde (2a–2f) and malonic acid in acetic acid and piperidine into cinnamic acid (3a–3f) in 77 to 89% followed by its reduction with PdCl2 in the biphase of formic acid and aqueous sodium hydroxide is reported under microwave irradiation which utilizes short reaction time ranging 5 to 7 min to provide 1a–1f in moderate to high yield (69–86%) depending upon methoxy, methylenedioxy, and hydroxy groups present at the phenyl ring.
|
|
| Publisher |
The Chemical Society of Japan
|
|
| Date |
2003
|
|
| Type |
Article
PeerReviewed |
|
| Relation |
http://www.csj.jp/journals/chem-lett/index.html
http://ihbt.csircentral.net/720/ |
|
| Identifier |
Sharma , A and Joshi, B P and Sinha, Arun K (2003) A Rapid and Efficient Microwave-Assisted Synthesis of Substituted 3-Phenylpropionic Acids from Benzaldehydes in Minutes. Chemistry Letters, 32 (12). pp. 1186-67. ISSN 0366-7022
|
|