A Synergic Blend of Newly Isolated Pseudomonas mandelii KJLPB5 and [hmim]Br for Chemoselective 2 degree Aryl Alcohol Oxidation in H2O2: Synthesis of Aryl Ketone or Aldehydes via Sequential Dehydration-Oxidative C=C Cleavage
IR@CSIR-IHBT
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Title |
A Synergic Blend of Newly Isolated Pseudomonas mandelii KJLPB5 and [hmim]Br for Chemoselective 2 degree Aryl Alcohol Oxidation in H2O2: Synthesis of Aryl Ketone or Aldehydes via Sequential Dehydration-Oxidative C=C Cleavage |
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Creator |
Sharma , N
Sharma, U K Salwan, R Kasana , Ramesh C Sinha, Arun K |
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Subject |
Microbiology
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Description |
Pseudomonas mandelii KJLPB5 is reported for the oxidation of aryl alcohols in ionic liquid [hmim]Br (1-hexyl-3-methyl imidazolium bromide) with H2O2. With a slight alteration of reaction conditions, the developed protocol leads either to (i) chemoselective oxidation of 2 degree aryl alcohols over 1 degree and aliphatic counterparts or (ii) direct one pot-two step sequential conversion of 2 degree aryl alcohols into corresponding one or two carbons shorter aryl aldehydes through oxidative cleavage pathway, thus providing a new facet to metal-free oxidations. The key operational parameters such as substrate concentration, incubation temperature, incubation time, ionic liquid type and ionic liquid concentration are also optimized. |
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Date |
2011
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://ihbt.csircentral.net/910/1/A_Synergic_Blend_of_Newly_Isolated_Pseudomonas_mandelii.pdf
Sharma , N and Sharma, U K and Salwan, R and Kasana , Ramesh C and Sinha, Arun K (2011) A Synergic Blend of Newly Isolated Pseudomonas mandelii KJLPB5 and [hmim]Br for Chemoselective 2 degree Aryl Alcohol Oxidation in H2O2: Synthesis of Aryl Ketone or Aldehydes via Sequential Dehydration-Oxidative C=C Cleavage. Catal Lett, 141. pp. 616-622. |
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Relation |
http://ihbt.csircentral.net/910/
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