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Chemical composition and antimicrobial activity of the leaf essential oil of Skimmia laureola growing wild in Jammu and Kashmir, India

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Title Chemical composition and antimicrobial activity of the leaf essential oil of
Skimmia laureola growing wild in Jammu and Kashmir, India
 
Creator Shah, Wajaht A
Dar, Mohd Yousuf
Zagar, M. Iqbal
Agnihotri, Vijai K
Qurishi, M.A
Singh , Bikram
 
Subject Natural Product Chemistry
 
Description The analysis of Skimmia laureola hydrodistillate by gas chromatography coupled
with mass spectrometry revealed the presence of 20 constituents, representing
94.6% of the total oil. The major constituents of oil were linalyl acetate (33.0%),
linalool (25.0%), limonene (8.1%), α-terpineol (5.9%) and geranyl acetate
(5.9%). The monoterpene (93.4%) rich essential oil was evaluated for its
antibacterial and antifungal activities against seven microorganisms by agar
diffusion and microdilution methods. The oil showed appreciable antimicrobial
effects against all Gram-positive bacteria tested, including methicillin-resistant
Staphylococcus aureus and Staphylococcus epidermidis with MIC values 32 and
64 mgmL-1, respectively. The oil also exhibited strong fungicidal activity
against Aspergillus niger and Penicillium chrysogenum with MIC value in the
range 32–16 mgmL-1. The oil could be used in the formulation of antimicrobial
agents.
 
Date 2012
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://ihbt.csircentral.net/1240/1/46_Chemical_composition_and.pdf
Shah, Wajaht A and Dar, Mohd Yousuf and Zagar, M. Iqbal and Agnihotri, Vijai K and Qurishi, M.A and Singh , Bikram (2012) Chemical composition and antimicrobial activity of the leaf essential oil of Skimmia laureola growing wild in Jammu and Kashmir, India. Natural Product Research. pp. 1-5.
 
Relation http://ihbt.csircentral.net/1240/