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Direct One-Pot Cobalt(II) Phthalocyanine Catalyzed Synthesis of N-Substituted Isoindolinones

IR@CSIR-IHBT

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Field Value
 
Title Direct One-Pot Cobalt(II) Phthalocyanine Catalyzed
Synthesis of N-Substituted Isoindolinones
 
Creator Kumar, Vishal
Sharma, Upendra
Singh , Bikram
Kumar, Neeraj
 
Subject Natural Product Chemistry
 
Description A direct one-pot synthetic approach is described wherein cobalt(II) phthalocyanine (CoPc) catalyzed reductive amination
of 2-carboxybenzaldehyde, followed by intramolecular amidation afforded N-substituted isoindolinones. The method
used diphenylsilane as reducing agent in ethanol. High chemoselectivity with excellent yield was obtained in most of the studied substrates.
 
Date 2012
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://ihbt.csircentral.net/1350/1/137_Direct_one-pot.pdf
Kumar, Vishal and Sharma, Upendra and Singh , Bikram and Kumar, Neeraj (2012) Direct One-Pot Cobalt(II) Phthalocyanine Catalyzed Synthesis of N-Substituted Isoindolinones. Australian Journal of Chemistry, 65. pp. 1594-1598.
 
Relation http://ihbt.csircentral.net/1350/