Expression dynamics of metabolic and regulatory components across stages of panicle and seed development in indica rice
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Title |
Expression dynamics of metabolic and regulatory components across stages of panicle and seed development in indica rice
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Creator |
Sharma, Rita
Agarwal, Pinky Ray, Swatismita Deveshwar, Priyanka Sharma, Pooja Sharma, Niharika Nijhawan, Aashima Jain, Mukesh Singh, Ashok Kumar Singh, Vijay Pal Khurana, Jitendra Paul Tyagi, Akhilesh K. Kapoor, Sanjay |
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Subject |
Development
Expression Meta-analysis Metabolic pathways Panicle Promoter Seed Transcription factors |
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Description |
Accepted date: 6 March 2012
Carefully analyzed expression profiles can serve as a valuable reference for deciphering gene functions. We exploited the potential of whole genome microarrays to measure the spatial and temporal expression profiles of rice genes in 19 stages of vegetative and reproductive development. We could verify expression of 22,980 genes in at least one of the tissues. Differential expression analysis with respect to five vegetative tissues and preceding stages of development revealed reproductive stage-preferential/-specific genes. By using subtractive logic, we identified 354 and 456 genes expressing specifically during panicle and seed development, respectively. The metabolic/hormonal pathways and transcription factor families playing key role in reproductive development were elucidated after overlaying the expression data on the public databases and manually curated list of transcription factors, respectively. During floral meristem differentiation (P1) and male meiosis (P3), the genes involved in jasmonic acid and phenylpropanoid biosynthesis were significantly upregulated. P6 stage of panicle, containing mature gametophytes, exhibited enrichment of transcripts involved in homogalacturonon degradation. Genes regulating auxin biosynthesis were induced during early seed development. We validated the stage-specificity of regulatory regions of three panicle-specific genes, OsAGO3, OsSub42, and RTS, and an early seed-specific gene, XYH, in transgenic rice. The data generated here provides a snapshot of the underlying complexity of the gene networks regulating rice reproductive development. This work was supported by Department of Biotechnology, Ministry of Science & Technology, Government of India (Project No. BT/AB/FG-I(PH-II)(4)/2009). We acknowledge Dr. Ramesh Hariharan and his team at Strand LS Bengaluru, India for their help in microarray data analysis and Ms. Manupriya for providing the list of transcription factor family genes in rice. Senior Research fellowship by the Council for Scientific and Industrial Re- search (CSIR) to R.S., S.R., P.D, M.J., A.N., and P.S. and University Grants Commissions (UGC) fellowship to P.A. are acknowledged. |
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Date |
2015-10-29T07:03:32Z
2015-10-29T07:03:32Z 2012 |
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Type |
Article
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Identifier |
Funct. Integr. Genomics, 12(2): 229-248
1438-7948 http://link.springer.com/article/10.1007%2Fs10142-012-0274-3 http://172.16.0.77:8080/jspui/handle/123456789/279 |
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Language |
en_US
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Publisher |
Springer
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