The regulation of the Z- and G-box containing promoters by light signaling components, SPA1 and MYC2, in Arabidopsis
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Title |
The regulation of the Z- and G-box containing promoters by light signaling components, SPA1 and MYC2, in Arabidopsis
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Creator |
Gangappa, Sreeramaiah N.
Maurya, Jay P. Yadav, Vandana Chattopadhyay, Sudip |
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Subject |
Arabidopsis
SPA1 MYC2 G-Box Z-Box Light Signaling |
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Description |
Accepted date: March 18, 2013
Although many transcription factors and regulatory proteins have been identified and functionally characterized in light signaling pathways, photoperception to transcription remains largely fragmented. The Z-box is one of the LREs (Light responsive elements) that plays important role in the regulation of transcription during light-controlled Arabidopsis seedling development. The involvement of photoreceptors in the modulation of the activity of the Z-box containing promoters has been demonstrated. However, the role of downstream signaling components such as SPA1 and MYC2/ZBF1, which are functionally interrelated, remains unknown. In this study, we have investigated the regulation of the Z-box containing synthetic and native promoters by SPA1 and MYC2 by using stable transgenic lines. Our studies suggest that SPA1 negatively regulates the expression of CAB1 native promoter. MYC2 negatively regulates the activity of Z- and/or G-box containing synthetic as well as native promoters irrespective of light quality. Moreover, MYC2 negatively regulates the expression of Z/G-NOS101-GUS even in the darkness. Furthermore, analyses of tissue specific expression in adult plants suggest that MYC2 strongly regulates the activity of Z- and G-box containing promoters specifically in leaves and stems. In roots, whereas MYC2 positively regulates the activity of the Z-box containing synthetic promoter, it does not seem to control the activity of the G-box containing promoters. Taken together, these results provide insights into SPA1- and MYC2-mediated transcriptional regulation of the Z- and G-box containing promoters in light signaling pathways. This work is supported by J. C. Bose National Fellowship Award Grant from Department of Science and Technology, Government of India (http://www. dst.gov.in/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
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Date |
2015-11-03T06:14:49Z
2015-11-03T06:14:49Z 2013 |
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Type |
Article
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Identifier |
PLoS One, 8(4): e62194
1932-6203 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062194 http://172.16.0.77:8080/jspui/handle/123456789/305 |
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Language |
en_US
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Publisher |
PLOS
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