Induction of senescence and identification of differentially expressed genes in tomato in response to monoterpene
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Title |
Induction of senescence and identification of differentially expressed genes in tomato in response to monoterpene
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Creator |
Ghosh, Sumit
Singh, Upendra Kumar Meli, Vijaykumar S. Kumar, Vinay Kumar, Anil Irfan, Mohammad Chakraborty, Niranjan Chakraborty, Subhra Datta, Asis |
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Subject |
Tomato
Monoterpene Senescence Differentially Expressed Genes |
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Description |
Accepted date: August 21, 2013
Monoterpenes, which are among the major components of plant essential oils, are known for their ecological roles as well for pharmaceutical properties. Geraniol, an acyclic monoterpene induces cell cycle arrest and apoptosis/senescence in various cancer cells and plants; however, the genes involved in the process and the underlying molecular mechanisms are not well understood. In this study, we demonstrate that treatment of tomato plants with geraniol results in induction of senescence due to a substantial alteration in transcriptome. We have identified several geraniol-responsive protein encoding genes in tomato using suppression subtractive hybridization (SSH) approach. These genes comprise of various components of signal transduction, cellular metabolism, reactive oxygen species (ROS), ethylene signalling, apoptosis and DNA damage response. Upregulation of NADPH oxidase and antioxidant genes, and increase in ROS level after geraniol treatment point towards the involvement of ROS in geraniol-mediated senescence. The delayed onset of seedling death and induced expression of geraniol-responsive genes in geraniol-treated ethylene receptor mutant (Nr) suggest that geraniol-mediated senescence involves both ethylene dependent and independent pathways. Moreover, expression analysis during tomato ripening revealed that geraniol-responsive genes are also associated with the natural organ senescence process. The sequencing facility at the National Institute of Plant Genome Research is acknowledged. SG, UKS, VSM and VK have received fellowship from the Council of Scientific and Industrial Research. AK and MI have received fellowship from the National Institute of Plant Genome Research and the University Grant Commission, respectively. |
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Date |
2015-11-03T09:39:34Z
2015-11-03T09:39:34Z 2013 |
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Type |
Article
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Identifier |
PLoS One, 8(9): e76029
1932-6203 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076029 http://172.16.0.77:8080/jspui/handle/123456789/310 |
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Language |
en_US
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Publisher |
PLOS
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