Catharanthus roseus mitogen-activated protein kinase 3 confers UV and heat tolerance to Saccharomyces cerevisiae
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Title |
Catharanthus roseus mitogen-activated protein kinase 3 confers UV and heat tolerance to Saccharomyces cerevisiae
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Creator |
Raina, Susheel Kumar
Wankhede, Dhammaprakash Pandhari Sinha, Alok Krishna |
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Subject |
Catharanthus roseus
CrMPK3 abiotic stress UV heat cold Saccharomyces cerevisiae |
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Description |
Accepted date: 30 Oct 2012
Catharanthus roseus is an important source of pharmaceutically important Monoterpenoid Indole Alkaloids (MIAs). Accumulation of many of the MIAs is induced in response to abiotic stresses such as wound, ultra violet (UV) irradiations, etc. Recently, we have demonstrated a possible role of CrMPK3, a C. roseus mitogen-activated protein kinase in stress-induced accumulation of a few MIAs. Here, we extend our findings using Saccharomyces cerevisiae to investigate the role of CrMPK3 in giving tolerance to abiotic stresses. Yeast cells transformed with CrMPK3 was found to show enhanced tolerance to UV and heat stress. Comparison of CrMPK3 and SLT2, a MAPK from yeast shows high-sequence identity particularly at conserved domains. Additionally, heat stress is also shown to activate a 43 kDa MAP kinase, possibly CrMPK3 in C. roseus leaves. These findings indicate the role of CrMPK3 in stress-induced MIA accumulation as well as in stress tolerance. We thank Dr. Debasis Chattopadhyay, NIPGR, New Delhi for providing yeast strain BCY123 and pYES2.1 vector. S.K.R. and D.P.W. thank Council of Scientific and Industrial Research and University Grant Commission, India for research fellowships. This work is supported by core grant of National Institute of Plant Genome Research, New Delhi, India from Department of Biotechnology, India. |
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Date |
2015-11-16T06:09:42Z
2015-11-16T06:09:42Z 2013 |
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Type |
Article
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Identifier |
Plant Signal. Behav., 8(1): 116-119
1559-2324 http://172.16.0.77:8080/jspui/handle/123456789/358 http://www.tandfonline.com/doi/abs/10.4161/psb.22716 10.4161/psb.22716 |
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Language |
en_US
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Publisher |
Taylor & Francis
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