Expanding frontiers in plant transcriptomics in aid of functional genomics and molecular breeding
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Title |
Expanding frontiers in plant transcriptomics in aid of functional genomics and molecular breeding
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Creator |
Agarwal, Pinky
Parida, Swarup K. Mahto, Arunima Das, Sweta Mathew, Iny Elizebeth Malik, Naveen Tyagi, Akhilesh K. |
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Subject |
Functional genomics
Microarray NGS RNA-seq Transcriptome |
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Description |
Accepted date: 01 OCT 2014
The transcript pool of a plant part, under any given condition, is a collection of mRNAs that will pave the way for a biochemical reaction of the plant to stimuli. Over the past decades, transcriptome study has advanced from Northern blotting to RNA sequencing (RNA-seq), through other techniques, of which real-time quantitative polymerase chain reaction (PCR) and microarray are the most significant ones. The questions being addressed by such studies have also matured from a solitary process to expression atlas and marker-assisted genetic enhancement. Not only genes and their networks involved in various developmental processes of plant parts have been elucidated, but also stress tolerant genes have been highlighted. The transcriptome of a plant with altered expression of a target gene has given information about the downstream genes. Marker information has been used for breeding improved varieties. Fortunately, the data generated by transcriptome analysis has been made freely available for ample utilization and comparison. The review discusses this wide variety of transcriptome data being generated in plants, which includes developmental stages, abiotic and biotic stress, effect of altered gene expression, as well as comparative transcriptomics, with a special emphasis on microarray and RNA-seq. Such data can be used to determine the regulatory gene networks, which can subsequently be utilized for generating improved plant varieties. A. M. and N. M. acknowledge the junior and senior research fellowship, respectively, from Council for Scientific and Industrial Research (CSIR) and S. D. and I. E. M. acknowledge the senior research fellowship from University Grants Commission (UGC). P. A., S. K. P., and A. K. T. thank the Department of Biotechnology (DBT), India for grants supporting research. |
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Date |
2015-11-26T09:36:59Z
2015-11-26T09:36:59Z 2014 |
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Type |
Article
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Identifier |
Biotechnol. J., 9(12): 1480-1492
1860-6768 http://172.16.0.77:8080/jspui/handle/123456789/390 http://onlinelibrary.wiley.com/doi/10.1002/biot.201400063/abstract 10.1002/biot.201400063 |
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Language |
en_US
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Publisher |
John Wiley & Sons Ltd
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