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Involvement of host regulatory pathways during geminivirus infection: a novel platform for generating durable resistance

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Title Involvement of host regulatory pathways during geminivirus infection: a novel platform for generating durable resistance
 
Creator Sahu, Pranav Pankaj
Sharma, Namisha
Puranik, Swati
Muthamilarasan, Mehanathan
Prasad, Manoj
 
Subject Antiviral compound
Cell cycle
Epigenetics
Geminivirus
Geminivirus–host interaction
Virus resistance
 
Description Accepted date: 21 October 2013
Geminiviruses are widely distributed throughout the world and cause devastating yield losses in almost all the economically important crops. In this review, the newly identified roles of various novel plant factors and pathways participating in plant–virus interaction are summarized with a particular focus on the exploitation of various pathways involving ubiquitin/26S proteasome pathway, small RNA pathways, cell division cycle components, and the epigenetic mechanism as defense responses during plant–pathogen interactions. Capturing the information on these pathways for the development of strategies against geminivirus infection is argued to provide the basis for new genetic approaches to resistance.
We are grateful to the Director, National Institute of
Plant Genome Research (NIPGR), New Delhi, India for providing us the
facilities. The authors’ works in this area are supported by the core grant
of NIPGR. We thank Dr. Senthil-Kumar Muthappa, NIPGR for critically
reading the manuscript. Ms. Namisha Sharma and Mr. Mehanathan
Muthamilarasan acknowledge the award of Junior Research Fellowship from Department of Biotechnology, New Delhi and University Grants
Commission, New Delhi, respectively.
 
Date 2015-12-23T06:06:58Z
2015-12-23T06:06:58Z
2014
 
Type Article
 
Identifier Funct. Integr. Genomics, 14(1): 47-58
1438-7948
http://172.16.0.77:8080/jspui/handle/123456789/447
http://link.springer.com/article/10.1007%2Fs10142-013-0346-z
10.1007/s10142-013-0346-z
 
Language en_US
 
Publisher Springer