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Multiple interactions between glucose and brassinosteroid signal transduction pathways in Arabidopsis are uncovered by whole-genome transcriptional profiling

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Title Multiple interactions between glucose and brassinosteroid signal transduction pathways in Arabidopsis are uncovered by whole-genome transcriptional profiling
 
Creator Gupta, Aditi
Singh, Manjul
Laxmi, Ashverya
 
Subject Arabidopsis
Glucose
Brassinosteroid
Signal Transduction Pathways
Whole-Genome Transcriptional Profiling
 
Description Accepted date: May 31, 2015
Brassinosteroid (BR) and glucose (Glc) regulate many common responses in plants. Here, we demonstrate that under etiolated growth conditions, extensive interdependence/overlap occurs between BR- and Glc-regulated gene expression as well as physiological responses. Glc could regulate the transcript level of 72% of BR-regulated genes at the whole-genome level, of which 58% of genes were affected synergistically and 42% of genes were regulated antagonistically. Presence of Glc along with BR in medium could affect BR induction/repression of 85% of BR-regulated genes. Glc could also regulate several genes involved in BR metabolism and signaling. Both BR and Glc coregulate a large number of genes involved in abiotic/biotic stress responses and growth and development. Physiologically, Glc and BR interact to regulate hypocotyl elongation growth of etiolated Arabidopsis (Arabidopsis thaliana) seedlings in a dose-dependent manner. Glc may interact with BR via a hexokinase1 (HXK1)-mediated pathway to regulate etiolated hypocotyl elongation. Brassinosteroid insensitive1 (BRI1) is epistatic to HXK1, as the Glc insensitive2bri1-6 double mutant displayed severe defects in hypocotyl elongation growth similar to its bri1-6 parent. Analysis of Glc and BR sensitivity in mutants defective in auxin response/signaling further suggested that Glc and BR signals may converge at S-phase kinase-associated protein1-Cullin-F-box-transport inhibitor response1/auxin-related f-box-auxin/indole-3-acetic acid-mediated auxin-signaling machinery to regulate etiolated hypocotyl elongation growth in Arabidopsis.
This work was supported by the Department of Science and
Technology, Government of India (grant no. SR/FT/LS–102/2008),
a National Institute of Plant Genome Research core grant, and the
Council of Scientific and Industrial Research, India (research fellowships to A.G. and M.S.).
 
Date 2016-01-05T05:58:30Z
2016-01-05T05:58:30Z
2015
 
Type Article
 
Identifier Plant Physiol., 168(3): 1091-1105
1532-2548
http://172.16.0.77:8080/jspui/handle/123456789/507
http://www.plantphysiol.org/content/168/3/1091.long
10.1104/pp.15.00495
 
Language en_US
 
Publisher American Society of Plant Biologists