Chilli leaf curl virus infection highlights the differential expression of genes involved in protein homeostasis and defense in resistant chilli plants
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Title |
Chilli leaf curl virus infection highlights the differential expression of genes involved in protein homeostasis and defense in resistant chilli plants
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Creator |
Kushwaha, Nirbhay
Sahu, Pranav Pankaj Prasad, Manoj Chakraborty, Supriya |
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Subject |
Geminivirus
Transcriptome analysis Host gene expression Resistance Chilli Suppression subtractive hybridization |
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Description |
Accepted date: 17 January 2015
Geminiviruses have evolved with tremendous potential of recombination and possess the ability to manipulate several cellular processes of hosts. Chilli leaf curl virus (ChiLCV) is a monopartite Begomovirus (family Geminiviridae) which has emerged as a serious threat to chilli production worldwide. To date, development of resistant chilli varieties through conventional plant breeding techniques remains the major antiviral strategy. To explore the potential resistance factors in Capsicum annuum var. Punjab Lal, we performed a transcriptome analysis in ChiLCV-infected plants by exploiting the advantage of sensitivity and efficiency of suppression subtractive hybridization (SSH). Out of 480 clones screened, 231 unique expressed sequence tags (ESTs) involved in different cellular and physiological processes were identified. An interactome network of ChiLCV responsive differentially expressed genes revealed an array of proteins involved in key cellular processes including transcription, replication, photosynthesis, and defense. A comparative study of gene expression between resistant and susceptible chilli plants revealed upregulation of several defense-related genes such as nucleotide-binding site leucine-rich repeat (NBS-LRR) domain containing protein, lipid transfer protein, thionin, polyphenol oxidase, and other proteins like ATP/ADP transporter in the ChiLCV-resistant variety. Taken together, the present study provides novel insights into the transcriptomics of ChiLCV-resistant chilli plants. Nirbhay Kushwaha thanks the Council of Scientific and Industrial Research for providing a senior research fellowship. The authors gratefully acknowledge the financial support from the Department of Biotechnology, India (grant no. BT/PR/6504/AGII/106/878/ 2012). We thank Dr. V. K. Sharma and Ms. Mansi Bhardwaj for their suggestions and critical comments on the manuscript. |
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Date |
2016-01-14T09:33:21Z
2016-01-14T09:33:21Z 2015 |
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Type |
Article
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Identifier |
Applied Microbiology and Biotechnology, 99(11): 4757-4770
1432-0614 http://172.16.0.77:8080/jspui/handle/123456789/540 http://link.springer.com/article/10.1007%2Fs00253-015-6415-6 10.1007/s00253-015-6415-6 |
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Language |
en_US
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Publisher |
Springer
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