Plant ribosomal proteins, RPL12 and RPL19, play a role in nonhost disease resistance against bacterial pathogens
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Title |
Plant ribosomal proteins, RPL12 and RPL19, play a role in nonhost disease resistance against bacterial pathogens
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Creator |
Nagaraj, Satish
Senthil-Kumar, Muthappa Ramu, Vemanna S. Wang, Keri Mysore, Kirankumar S. |
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Subject |
nonhost resistance
VIGS ribosomal proteins Nicotiana benthamiana hypersensitive response plant defense |
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Description |
Accepted date: 11 December 2015
Characterizing the molecular mechanism involved in nonhost disease resistance is important to understand the adaptations of plant-pathogen interactions. In this study, virus-induced gene silencing (VIGS)-based forward genetics screen was utilized to identify genes involved in nonhost resistance in Nicotiana benthamiana. Genes encoding ribosomal proteins, RPL12 and RPL19, were identified in the screening. These genes when silenced in N. benthamiana caused a delay in nonhost bacteria induced hypersensitive response (HR) with concurrent increase in nonhost bacterial multiplication. Arabidopsis mutants of AtRPL12 and AtRPL19 also compromised nonhost resistance. The studies on NbRPL12 and NbRPL19 double silenced plants suggested that both RPL12 and RPL19 act in the same pathway to confer nonhost resistance. Our work suggests a role for RPL12 and RPL19 in nonhost disease resistance in N. benthamiana and Arabidopsis. In addition, we show that these genes also play a minor role in basal resistance against virulent pathogens. We thank Choong-Min Ryu for initiating the VIGS screen. We also thank Sumana Bhat and Srinivasa Rao Uppalapati for their critical comments during the preparation of this manuscript. This work was funded by the Samuel Roberts Noble Foundation and in part by a grant from Oklahoma Advancement for Science and technology (OCAST) to KM. |
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Date |
2016-01-20T09:27:37Z
2016-01-20T09:27:37Z 2015 |
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Type |
Article
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Identifier |
Front. Plant Sc., 6: 1192
1664-462X http://172.16.0.77:8080/jspui/handle/123456789/554 http://journal.frontiersin.org/article/10.3389/fpls.2015.01192/abstract 10.3389/fpls.2015.01192 |
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Language |
en_US
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Publisher |
Frontiers Media S.A.
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