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Application of molecular antiviral compounds: novel approach for durable resistance against geminiviruses

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Field Value
 
Title Application of molecular antiviral compounds: novel approach for durable resistance against geminiviruses
 
Creator Sahu, Pranav Pankaj
Prasad, Manoj
 
Subject Antiviral compounds
Broad spectrum resistance
Geminivirus
Virus–plant interactions
 
Description Accepted date: 22 January 2015
Both transgenic as well as traditional breeding approaches have not been completely successful in inducting resistance against geminiviruses in crop plants. This demands the utilization of non-viral, non-plant compounds possessing antiviral characteristics as an alternate and effective strategy for developing durable resistance against geminiviruses. In recent years, several antiviral molecules have been developed for the treatment of plant virus infections. These molecular antiviral compounds target various geminiviral-DNA and -protein via interacting with them or by cleaving viral RNA fragments. Applications of these proteins such as GroEL, g5g and VirE2 have also provided a convincing evidence of resistance against geminiviruses. Taking advantage of this information, we can generate robust resistance against geminiviruses in diverse crop plants. In this context, the present review provides epigrammatic information on these antiviral compounds and their mode of action in modulating virus infection.
 
Date 2016-01-21T09:34:30Z
2016-01-21T09:34:30Z
2015
 
Type Article
 
Identifier Mol. Biol. Rep., 42(7): 1157-1162
1573-4978
http://172.16.0.77:8080/jspui/handle/123456789/570
http://link.springer.com/article/10.1007%2Fs11033-015-3852-3
10.1007/s11033-015-3852-3
 
Language en_US
 
Publisher Springer