Unraveling the intricate nexus of molecular mechanisms governing rice root development: OsMPK3/6 and auxin-cytokinin interplay
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Title |
Unraveling the intricate nexus of molecular mechanisms governing rice root development: OsMPK3/6 and auxin-cytokinin interplay
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Creator |
Singh, Pallavi
Mohanta, Tapan Kumar Sinha, Alok Krishna |
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Subject |
Rice Root Development
OsMPK3/6 Auxin- Cytokinin Interplay |
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Description |
Accepted date: March 2, 2015
The root system is an imperative component of a plant, involved in water and nutrient acquisition from the soil. Any subtle change in the root system may lead to drastic changes in plant productivity. Both auxin and cytokinin are implicated in regulating various root developmental aspects. One of the major signaling cascades facilitating various hormonal and developmental allocations is the Mitogen Activated Protein Kinase (MAPK) cascade. Innumerable efforts have been made to unravel the complex nexus involved in rice root development. In spite of a plethora of studies, a comprehensive study aiming to decipher the plausible cross-talk of MAPK signaling module with auxin and cytokinin signaling components in rice is missing. In the present study, extensive phenomics analysis of different stages of rice roots; transcript profiling by qRT-PCR of entire gene family of MAPK, MAPKK and PIN genes; as well as protein level and activity of potential MAPKs was investigated using western and immuno kinase assays both on auxin and cytokinin treatment. The above study led to the identification of various novel rice root specific phenotypic traits by using GiA roots software framework. High expression profile of OsMPK3/6, OsMKK4/5 and OsPIN 1b/9 and their marked transcript level modulation in response to both auxin and cytokinin was observed. Finally, the protein levels and activity assay further substantiated our present findings. Thus, OsMPK3/6-OsMKK4/5 module is elucidated as the putative, key player in auxin-cytokinin interaction augmenting their role by differentially regulating the expression patterns of OsPIN 1b/9 in root development in rice. This study was supported by the Department of Biotechnology (DBT), Govt of India, New Delhi, DBT Sanction Order No.: BT/PR3298/ AGR/2/812/2011. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
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Date |
2016-01-22T09:59:07Z
2016-01-22T09:59:07Z 2015 |
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Type |
Article
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Identifier |
PLoS One, 10(4): e0123620
1932-6203 http://172.16.0.77:8080/jspui/handle/123456789/581 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123620 10.1371/journal.pone.0123620 |
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Language |
en_US
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Publisher |
PLOS
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